Mauricio Pochettino said Tottenham had lost Dele Alli in "one of the worst moments" with the midfielder until March.
Harry Kane should also miss the same period due to ankle ligament injuries and his absent Heung-Min for the Asian Cup. The Spurs do not have three key offensive players as they prepare for four games in the next 10 days, starting Thursday. Trip to Chelsea in the second leg of the Carabao Cup semi-final.
"Now we have to be positive, as with Harry Kane," said Pochettino. "Of course, we will miss him [Alli] for a long time.
"It's one of the worst moments because we have very busy games, but you know very well that for us the team is very important and it's a great opportunity for other players.
"Tomorrow [Moussa] Sissoko and Lucas [Moura] are in conflict. With [Victor] Wanyama, we'll see if he can be in contention for the FA Cup weekend. It's a very good news in recent days to recover Moussa and Lucas, and Wanyama is so close. "
Despite the Spurs' lack of offensive options, Pochettino does not intend to recall striker Vincent Janssen to his first-team team.
The Dutchman last played for the Spurs in August 2017 and the residents of North London remain eager to sell it for around £ 15 million.
"I think it's so clear that it's been a year and a half since it's not in our plans," said Pochettino.
"Eighteen months ago, we made the decision for him to try to find a different place to play because for different reasons, it did not work.This happens in football – the relationship between the player and the club does not work.You need to find the best solution.
"In the same way, we try to get him in shape as quickly as possible – he trains with the club under 23 at the club," trying to help him outdo himself, then trying to find a club where he can be happy. again and try to play, but here it is impossible.
"[Our relationship] it's fine. I see him every day in the locker room and at the restaurant. This is not a personal problem, it is the professional side. For different reasons, this professional relationship does not work and we have to find a solution. "